The International Headquarters encompasses a system of twelve departments, created to oversee the worldwide network of ACM ministries. Leaders from ACMs around the world serve as members in each department. The International Headquarters provides the structure through which ongoing missions are supported and united, and guides the development and growth of ACM missions on the foundation of the original vision of its founders.

1. Department of General Affairs- The department of the General Affairs is the overseeing department of Apostolos Campus Ministry. The purpose of the department of General Affiars is to administer over all departments, organize and develop new systems, and lend direction and support to all areas of ACM. This department schedules special events or meetings during which representatives gather to discuss the activities and progress of ACM internal structural development while factoring in the needs of global ministers. Networking with Christian leaders and organizations is also a primary focus of this department. The Department of General Affairs also has the responsibility to set up special committees when deemed necessary.

2. Secretariat- The Secretariat takes charge of daily operations that keep ACM running smoothly. From administering policy to record-keeping to facilitating activities, the Secretariat undertakes to connect members, employees, and visitors with the resources they are seeking. Secretariat workers keep notes and records of all online and offline conferences, archive past records, maintain current updates on all contact and member information for international branches, and post announcements from each department. The Secretariat is also responsible for interpreting and translating documents that are constantly flowing between chapters and offices around the world.

3. Missions Department- Driving ACM forward is our desire to reach students from all nations around the world. The Missions Department is where all other departments can see the fruit of their work. As Jesus said in the parable of the lost sheep, ACM Missions truly values each student preciously and seeks all over the globe to find one more soul thirsty for the living water that only Jesus can provide. The missions departments regularly challenges the other departments as it strives to meet its ever-expanding demands. At continental, regional, and local levels, the Missions Department drafts specific mission plans, records standards and goals set by various chapters and regions, and monitors missionary activities. Other responsibilities of the Missions Department are: to research the culture and society of countries and campuses and to develop mission guides; to direct pioneering activities and guide missionaries in VISA application procedures.

4. Education Department- The Education Department is one of the most important departments of ACM. It is responsible for guiding the leaders and the students and bringing the ACM statement of faith into practice. In order to do so, the Eduction Department is permanently seeking to improve its operating system. The Director of Education will hold regular conferences with other members of the education council to ensure that the mission tools and the word is always delivered in an organized manner. The Education Department is also in charge of developing lecture guides and other online and offline publications.

5. Finance Department- For Apostolos Campus Ministry to function well in the short and long term, a strong financial team has been set up. The Finance Department handles day-to-day financial operations, and, more importantly, creates annual budgets for the Headquarters in America and in all the other countries. It is in charge of gathering always new methods of funding and developing current forms of fundraising. The Financial Director is always in contact with other ministries and companies that can help support ACM. The Finance Departmentis a core department to ACM, especially in the support of pioneering and ongoing missions

6. Reporting Department- With Christian movements and mega-churches rapidly pressing to the forefront of the global Christian community, the Reporting Department wishes to accurately assess the current Christian situation on a worldwide scale and provide a context through which to view the impact of Apostolos Campus Ministry. To this end, our reports desire to find the most applicable and appropriate material for directing the lives of college students toward Jesus. On a local scale, ACM chapters have a reporting system through which they can share guidance and tips to each other and gain strength from one another. The Reporting Department enables international and regional websites, oversees and regional committees, and the establishment a global reporting network to be possible.

7. IP (Intercessory Prayer) Department- One of the fastest growing ministries is that of the trained prayer team, the members of which avail themselves to pray for others. Apostle Paul said:

"First of all, then, I urge that supplications, prayers, intercessions, and thanksgivings be made for everyone..." 1 Timothy 2:1

"Rejoice always, pray without ceasing, give thanks in all circumstances; for this is the will of God in Christ Jesus for you. Do not quench the Spirit." 1 Thessalonians 5:16-19

As the department of a campus ministry composed of numerous chapters all over the world, the ACM IP Department is to collect international goals and prayer topics, intercede and mediate for each nation through prayers, share visions and grace from prayers, and regulate prayer standards internationally. The vision of the IP Department is to watchfully pray and stand in the gap of each nation. Not only does the IP Department pray for the concerns of the mission, but it also strives to intercede for the missionaries in our community and in the work of world mission. The IP Department is the deparment behind-the-scenes, fighting in the frontlines of the spiritual battle with prayer weapons.

8. Web Department- During the last decade, Internet has emerged to become one of the prime sources of media and communication. Throughout history, the development of communication has aided the spread of the Gospel--Gutenberg's Printing Press and Luther's Reformation are the clearest examples. With web evangelism, a new way of reaching out through mass media, we hope to proclaim the good news of Jesus Christ have people accept Jesus as their personal Savior. With that goal, our Web Department consistently researches and actively participates in designing, maintaining, and advertising websites in order to maximize the effect of the web ministry. The commission of the Web Department is to build and maintain websites, create advanced web designs, and conduct research on website development.

9. Public Relations Department- The Public Relations Department acts as the public face of ACM that presents our dynamic atmosphere to those who wish to learn more about our community. Media presentations, press kits, newsletters, and other tools allow those who wish to learn more about ACM to understand the many aspects of what we do. The Public Relations Department also organizes personal, regional, and national meetings with Christian leaders and serves as the liaison in building relationships between ACM and other Christian organizations. It is the specific task of the Public Relations Department to oversee the establishment of the Board of Trustees, made up of members from the nations where ACM has chapters.

10. Publishing Department- The Publishing Department works closely with the Education Department in order to supply ACM members with the finest and most spiritually valuable resources to fulfill all mission needs. Not only does the Publishing Department work to provide original materials for education, but it also directly supports missions by designing and publishing all printed materials for ACM missions, including: membership cards, bulletins, offline newsletters, books, flyers, and business cards. Finally, the Publishing Department works internally within ACM to provide administrators with the manuals and materials that are necessary for standardizing mission structure and policy.

11. Culture Department- In many cases, university culture pushes students further away from God. But ACM promotes the Gospel message through the performing arts (music, dance, drama), and leads students toward Christ-centered culture in student life. Therefore culture is very crucial in ACM’s ministry as the medium for relaying the Truth to non-believers, as well as for uniting God’s people in worship, and utilizing the talents God has given His people to worshiping Him and making Him known.

12. Information Technology (IT) Department- Quick communication and data transfer are necessary to meet the global demands of ACM ministries. Precise communication is necessary between ministers in the field and ACM HQ in order for successful ministries to be established on an expanding number of campuses. The IT Department fills ACM needs for global infrastructure and information transfer. Another aspect of the IT Department is its research on possible methods to promote evangelism via Internet and technologies and organize contents and information to post electronically to the public.